KOSMD Consultitng, Inc. 

Your Partner In Wound Healing

We empower the medical provider to improve outcomes through knowledge & application of the latest in cutting edge technologies


We bring our expertise with the goal of helping providers to drive business growth and improved outcomes through implementation of the best in practice & proven cutting edge technologies.  We work with provider to establish  exceptional wound care services fully covered by Medicare, ensuring that every patient receives top-tier medical attention without financial strain. We help the provider to tailor treatment and integrate of state of the art innovative care to enhance overall health , minimize complications and accelerate recovery.

  • We provide 24/7 Support

  • We bring competitive pricing & bulk order discounts

  • We work closely to ensure a comprehensive understanding of the distinctions between products & how to incorporate

  • We provide prior authorization at the start and re-run monthly throughout membrane application process

  • We create a seamless ordering process & provide a HIPPA compliant portal for manage patient orders, track authorizations & shipping, etc.

  • We partner with leading billing companies to assist in authorizations and provide membrane billing services @ 2.9%

  • We bring a multifaceted approach to wound care that encompasses improved documentation & optimized healing conditions

  • We provide Quarterly Up=dates on new and existing membranes • ASP • National Fee Schedule • MUE

  • Next Day shipping if ordered prior to 3 pm c.s.t.

  • We Educate

  • We Coordinate

  • We Facilitate

Faster Healing • Better Healing • Improved Quality of Life

Faster Healing • Better Healing • Improved Quality of Life

Superior

Wound Healing with

Amniotic Membrane Allografts

The use of amniotic membrane allografts in wound treatment is a not only proven mechanism to accelerate wound healing but also to provide more durable repair. This cutting-edge approach to wound care, capitalizes on the addition of countless healing elements from the donated amniotic membrane. The donor membranes are stripped of their cellular elements that trigger immune response which reduces the inflammation and scarring, while providing elements to provide scaffold for cellular ingrowth and stimulate improve blood supply. Serving as a temporary protective layer, the amniotic allograft accelerates healing and wards off infection.

Proteins • More Collagen • More Fibrin • More Elastin • More Cytokines • More Growth Factors •

Proteins • More Collagen • More Fibrin • More Elastin • More Cytokines • More Growth Factors •

AMNIOTIC MEMBRANES IMPROVE WOUND HEALING BY PROVIDING:

Top Multi-layered Dehydrated Amniotic Membrane Allographs

  • Protective Covering

  • Immunogenicity

  • Angiogenesis

  • Scaffold

  • Growth Factors

No statements or implied treatments on this advertisement have been evaluated or approved by the FDA. This advertisement contains no medical advice.
All statements and opinions provided by this advertisement are provided for educational and informational purposes only and is not intended to diagnose nor treat any conditions. SS-009-RevA 10-2021.

Portfolio of Amniotic Membrane Allografts

Portfolio of Amniotic Membrane Allografts

Activate Matrix Q4301

$1934.29 ASP • 480 MUE

Lypholyzed Human Amniotic Membrane (DDHAM)

Allograft Sizes

  • 1×2 cm –  ACT-27212

  • 2×2 cm- ACT-27222

  • 2×3 cm – ACT-27223

  • 2×4 cm –  ACT-27224

  • 4×4 cm – ACT-27244

  • 4×6 cm –  ACT-27246

  • 4×8 cm –  ACT-27248

Use of XCell Amnio Matrix:

  • Diabetic Foot Ulcers (DFUs),

  • Venous Leg Ulcers (VLUs),

  • Pressure/Sacral Wounds,

  • Lacerations

  • MOHS

Allograft Sizes

  • 7×7 cm –  ACT-27277

  • 8x12cm –  ACT-27812

  • 9×20 cm –  ACT-27920

  • 12×20 cm – ACT-27122

  • 16×20 cm – ACT-27162

  • 20×20 cm – ACT-27202

  • 24×20 cm – ACT-27242

Tissue Harvest Protocol

Donor tissue is obtained through a full-term birth consent program in partnership with FDA regulated and accredited recovery organizations. Maternal screening includes:

  • Hepatitis B core Anitgen (HBcAg)

  • Hepatitis C antibodies (HCV Ab)

  • Human Immunodeficiency Virus

  • 1/O/2 antibodies (HIV-1/O/2 Ab)

  • Human T-lymphotrophic virus I/II (HTLV-I/II)

Activate™ Placental-Derived Allograft is processed in an ISO Class 5 environment.

3 Layered Amniotic Allograft Amnion • Sponge • Chorion

  • Gentle, non-oxidative dehydration process.

  • Minimized protein denaturing

  • Preserve structural integrity of the extracellular matrix

  • Terminally Sterilized

  • 5 yr shelf life

Xcell Amnio Matrix. Q4280

$2060.39 ASP • 180 MUE

Lypholyzed Human Amniotic Membrane (DDHAM)

Allograft Sizes

  • 6mm

  • 9mm

  • 12 mm disc

  • 2 ×2 cm

  • 2 x 4 cm

  • 4 x 4 cm

  • 4 x 7 cm

  • 10 x10 cm

  • 10 x 20 cm

Product Code

  • XAM006

  • XAM0006

  • XAM0012

  • XAM0202

  • XAM0204

  • XAM0404

  • XAM0407

  • XAM1010

  • XAM10220

Use of XCell Amnio Matrix:

  • Diabetic Foot Ulcers (DFUs),

  • Venous Leg Ulcers (VLUs),

  • Pressure/Sacral Wounds,

  • Lacerations

  • MOHS

Advanced Processing

•DryFlex® Processing

  • Retains the components found in human amniotic tissue1

  • Excellent handling and non-side specific application

  • Molds and conforms upon application

  • Room temperature storage

  • 5-year shelf life

UPC Code

  • 860011420798

  • 850059651001

  • 850059651018

  • 860011420750

  • 860011420767

  • 860011420774

  • 860011420781

  • none

  • none

SimpliMax- Q4341

$3525 National Fee Schedule

Dual-Layer Dehydrated Amniotic Membrane

Dual Layered Membrane

Placental tissue allograft composed of dual layer amnion

  • Non-side specific orientation for application

  • Thicker membrane for deep wounds or exposed anatomy that can be easily positioned or repositioned for improved conformity

  • Enhanced tensile strength, adheres well, and easy to apply

  • Can be used in a hydrated or dehydrated state

  • Retains important major structural proteins and ECM biochemicals that are naturally present in placental tissue

UPC

  • 860013115500

  • 860013115524

  • 860013115548

  • 860013115517

  • 860013115531

  • 860013115555

  • 860013115562

Advanced Processing

• Terminally sterilized using gamma irradiation to meet the Sterility Assurance Level of SAL of 1x10-6

• Extensive Donor Screening

• Tissue Processing within 24 hours of acquisition

•

Ease of Use

• EITHER side placed onto wound

• Effective with or without hydration

• DURABILE Enhanced Tensile Strength

• Thickness allows for easy handling & securing

• 5 yr shelf life

Use of SimpliMax:

  • Diabetic Foot Ulcers (DFUs),

  • Venous Leg Ulcers (VLUs),

  • Pressure/Sacral Wounds,

  • Lacerations

  • Burn injuries

Reference #

  • SMAX AA 0202

  • SMAX AA 0203

  • SMAX AA 0404

  • SMAX AA 0406

  • SMAX AA 0408

  • SMAX AA 1010

  • SMAX AA 2024

Sizes

  • 2cmx2cm

  • 2cmx3cm

  • 4cmx4cm

  • 4cmx6cm

  • 4cmx8cm

  • 10cmx10cm

  • 20cm x 24cm

Benefits of SimpliMax

  • Protective covering & barrier

  • Scaffold: Extracellular Matrix potentiates the (2) migration and adhesion of resident cells

  • Enriched with Cytokines & Growth Factors (3)

  • Anti-inflammatory: L-1ra, IL-4, IL-6, IL-10

  • Angiogenic: VEGF, TGF-Beta, EGF, PDGF

  • Cell Proliferation: IGF-1, KGF

  • Antibacterial: MIP

SimpliMax is packaged as a sterile product in sealed, single-use pouches. SimpliMax is processed in compliance with all current Good Tissue Practices as mandated by the United States Food and Drug Administration and the
American Association of Tissue Banks.
Only tissues from donors meeting the prescribed criteria are processed for manufacturing of SimpliMax

Infectious Disease Screened In Blood Specimens Of Donor

• HTLV I/II, HIV (NAT), HBV (NAT), HCV (NAT), HIV-1/2 antibody, Hepatitis B surface antigen, Hepatitis B core antibody (Total) • Hepatitis C antibody, Malaria, Syphilis, WNV (NAT)

AmnioAmp-MP Q4250

$2850 National Fee Schedule • 24 MUE

Decellularized Dehydrated Human Amniotic Membrane (DDHAM)

Dual Layered Membrane:

  • Minimally Manipulated

  • Dehydrated Formulated with patented PūrAMP Process™

  • retains nutrient growth factors that are essential for signaling

  • Preservation of the extracellular matrix (ECM), regulatory proteins

  • Removal of blood contaminants

  • E-Beam sterilization

  • 1 yer shelf life

Allograft Sizes

  • 2 x 3 cm

  • 2 × 4 c m

  • 2 × 6 cm

Cellular Benefits

  • Contains cytokines - epidermal, keratinocyte, hepatocyte, and Fibroblast growth factors, fibronectin, laminins, Type 1 & 2 Collagen extracellular matrix

    • Non-immunogenic,anti-inflammatory effect and reduces wound desiccation

Product Code

  • SB1000

  • SB1001

  • SB1002

AmnioAMP-MP approved chronic wounds types:

  • Diabetic Foot Ulcers (DFUs),

  • Venous Leg Ulcers (VLUs),

  • Pressure/Sacral Wounds,

  • Lacerations

  • Burn injuries

  • Partial and full-thickness wounds

  • Acute and chronic wound

  • Arterial insufficiency wounds,

  • Wounds with exposed tendon, muscle, and bone. 

Advanced Processing

• Terminally sterilized using electron-beam irradiation to meet the Sterility Assurance Level of SAL

• Extensive Donor Screening

• Tissue Processing within 24 hours of acquisition

Allograft Sizes

  • 3×8 cm

  • 4 ×4 cm

  • 2 ×6 cm

  • 16 mm Disk

Product Code

  • SB1003

  • SB1004

  • SB1005

  • SB1007

Benefits of AmnioAMP-MP

  • Protective covering & barrier

  • Immunogenicity: Amniotic is Non-immunologic (1)

  • Scaffold: Extracellular Matrix potentiates the (2) migration and adhesion of resident cells

  • Enriched with Cytokines & Growth Factors (3)

ESANO ACA- Q4275

$2652 National Fee Schedule * 480 MUE

Esano ACA is a dehydrated 3-Layer Aniotic Membrane for management of complex wounds.

3 Layered Membrane

• Amnion • Chorion • Amnion

• Enables Omnidirectional/Side Agnostic usage

• Structural Proteins & Extracellular Biochemicals

• All-Natural Cytokines & Growth Factors

Allograft Sizes

  • 2 x 2 cm

  • 2 × 3 c m

  • 2 ×4 cm

Product Code

  • EsanoACA-0202

  • EsanoACA-0203

  • EsanoACA-0204

Esano ACA approved chronic wounds types:

  • Diabetic Foot Ulcers (DFUs),

  • Venous Leg Ulcers (VLUs),

  • Pressure/Sacral Wounds,

  • Lacerations

  • Burn injuries

Ease of Use

• EITHER side placed onto wound

• Effective with or without hydration

• DURABILE Enhanced Tensile Strength

• Thickness allows for easy handling & securing

• 5 yr shelf life

Advanced Processing

• Terminally sterilized using electron-beam irradiation to meet the Sterility Assurance Level of SAL

• Extensive Donor Screening

• Tissue Processing within 24 hours of acquisition

• Contains cytokines - epidermal, keratinocyte, hepatocyte, and Fibroblast growth factors

• Non-immunogenic,anti-inflammatory effect and reduces wound desiccation

Allograft Sizes

  • 4 ×4 cm

  • 4 ×6 cm

  • 4 ×8 cm

Product Code

  • EsanoACA-0404

  • EsanoACA-0406

  • EsanoACA-0408

Benefits of Esano ACA

  • Protective covering & barrier

  • Immunogenicity: Amniotic is Non-immunologic (1)

  • Scaffold: Extracellular Matrix potentiates the (2) migration and adhesion of resident cells

  • Enriched with Cytokines & Growth Factors (3)

[1] Park C, Y, Kohanim S, Zhu L, Gehlbach P, L, Chuck R, S: Immunosuppressive Property of Dried Human Amniotc Membrane. Ophthalmic Res 2009;41:112-113. doi:10.1159/000187629.

[2)Thepresenceofextracellularmatrixw a sconfirmedb yinternalmeasurements of collagen (Sirius Red, Chondrex) a n d Hyaluronic Acid (Hyaluronan Quantkine ELISAKit,R&DSystems).|

[3)Thepresenceofgrowthfactorsconfirmedby3rdpartytestngusing Fluorescent Multplex ELISA (Quantbody® Human Growth Factor Array, Ray BioTech).

(4] Oyen ML, Cook RF, Calvin SE. Mechanical failure of human fetal membrane tissues. J MaterSciMaterMed2004;15:651-658.

[5] Chua WK, Oyen ML. Do w e know the strength of the chorioamnion? Acritical review and analysis. Eur J Obstet Gyn Reprod Biol 2009; 144(Suppl 1): S128-133.

[6Data on File

Esano ACA is manufactured under stringent and high-quality processes in state-of-the-art American Association of Blood Banks (AABB) and American Association of Tissue Banks (AATB) accredited facilities. Evolution Biologic is an FDA-registered biologics company creating human connective tissue matrix technologies. Sourced from C-Section donors from Tissue Banks with Tissue Reference Group (TRG) Certification and in accordance with FDA regulations under 21 CFRPart 1271 ensuring blood testing resulting in clearance of any HIV, HBsAg, HBc Total, HCV, and RPR comorbidities.

Dermabind TL Q 4225

Logo of Healthtech wound care the manufacturer of Dermabind TL and Dermabind dm dehydrated amniotic membrane cellular 3 layer

3 Layered Amniotic Membrane: Amnion • Sponge • Chorion

Preserved in dehydrated DermaBind allograft. Including cytokines, collagen matrix, glycoproteins, glycosaminoglycans. The proprietary preservation process of Dermabind is thought to increase the quantity of growth factors in this allograft, boasting the presence of 640 healing elements including: elastin, growth factors, fibrin, collagen & cytokines.

The Sponge layer contains hyaluronic acid;, TGF-B: transforming growth factor; HDF: Hepatocyte derived growth factor; Interleukin -1 antagonists.

FDA 361 DESIGNATED PRODUCT Dermabind TLTM Allograft

By not disrupt the natural state of the placental tissue in our manufacturing process, we deliver an allograft option that is intact from its original state. The DermaBind TL allograft product is the closest to the original state of the biomaterial and the original intent of the 361-product description for minimal manipulation and homologous use. This is also reinforced by our manufacturing process. https://www.fda.gov/media/109176/download

  1. Regulatory Considerations for Human Cells, Tissues, and Cellular and Tissue Based Products: Minimal Manipulation and Homologous Use

  2. 21 CFR Part 1271.10(a):

Image of the Dermabind Triple Layer Amniotic Membrane

Dermabind: Triple Layer Amniotic Membrane Allograft

  • Dehydrated, intact placental wound cover.

  • No separation of the amnion, intermediate and chorion layers

  • Preserved intermediate layer

  • Greatest concentration of proteins, cytokines, collagens, and glycoproteins

Dermabind : Natural Biologic Barrier

  • Terminally Sterilized using Gamma Irradiation

  • Never Frozen

  • Completely Free of Preservatives

  • Non-Immunogenic

    • Maintains Membrane Shape

    • Protects Membrane Protein

    • Enhance Function as Biologic Dressing

Dermabind: Preserved Natural State of the Placenta

  • Minimally Manipulated

  • No chemicals during dehydration

  • No antibiotics during processing

  • Eliminates risk of antibiotic-resistant bacteria

  • Eliminates risk of residual irritants

  • Eliminates risk of chemical denaturation of protein.

Can be applied in layers

  • Holds sutures well

  • Easy to handle

Dermabind: Thickest Homologous Allograft

1000 microns/1 mm

  • 1000 microns/1 mm

  • vs. Single layer is 150 microns thin = 1/6 of a triple layer

  • vs. Dual Layer is 300-400 microns thin:

    • A single layer that is folded back onto itself

    • Amnion and chorion layers.

    • DermaBind Triple Layer

    • Goo

Quality Assurance

  • DermaBind TL is manufactured under cGMP, cGTP, and ISO 13485 requirements and is processed from donors with normal, full-term pregnancies.

  • Each donor is carefully screened for comprehensive medical and social histories and is tested according to FDA requirements for Relevant Communicable Diseases.

  • Most placenta donors reside in Salt Lake City with higher statistics of healthier lifestyles and a very

Clean Processing

  • We don’t use antibiotics or harsh chemicals.

  • Our aseptic process takes care of this in the cleaning

    stage.

  • No soaps or chemicals used to clean the product,

    therefore no need to remove these later.

Drying Process

  • By using an Evaporative Dryer, we are able to keep the structure of the membrane and provide space.

  • We fluff up the intermediate layer and dry it so the body can use the scaffolding and space for better use in the patient’s treatment regimen.

  • Other allografts do not have this space

Radiation Process

  • The DermaBind radiation process is much less harsh due to our first steps for cleaning.

  • We use 17.5 kilogray, others can be known to use 25 kilogray.

  • The protein structure of the biomaterial can be negatively affected due to the use of that much radiation.

“The remarkable advantage I’ve discovered with the DermaBind TL Allograft is the elimination of the need for skin grafts, significantly expediting the healing process by tenfold or more. It’s truly transformative. DermaBind TL is healing even better than the dual layer I have used in the past.

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